Vaccine – Gung Ho

Every time I hear a British Politician or read a British Newspaper bragging about how well the vaccine roll out is going, I think to myself what fools. Not only this they diss the EU. They are talking as if coronavirus is a done deal, it is sorted, and all will be fine and dandy. There is a part of me that thinks “do not tempt fate”.  They are very nearly promising that it is all over. This wishful thinking and bigging up is in marked contrast to the press here. But the fat lady has not yet sung, so to speak.

 The figures here are excerpted from a preprint , a not yet peer reviewed, article:

 “Circulating SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity.”

from medRxiv.

{humoral immunity is antibody-mediated immunity}

The virus continues to mutate, here the purple is the British strain, which is mutating a lot, the red is the South African strain, and the yellow and orange are Brazilian. The “British” virus is rampant in Europe now.

The Brazilian P.1 and P.2 strains can reinfect people who have already had the earlier version of covid 19. A couple of the vaccines in preliminary data have been shown to have less efficacy against these Brazilian and South African strains. But this elephant in the room is not mentioned. The wonderful surge testing will root them out! All hail the great vaccine roll-out we shall be free soon.

The two viruses on the right here are SARS-CoV-1 and a related bat coronavirus. These are different from SARS-CoV-2 only sharing about 75% of the make up with it.

The P.1 and P.2 mutants come from Manaus in the Amazon. There is a strange sense that we burn and destroy the Amazon rain forest. It is in our cells there that the virus mutates, perhaps as karma. Until there is no longer a significant number of infected people, there will be mutations. The more people infected the more mutations there will be. It is a numbers game.

So, the UK can brag about its roll-out, but the virus will “breed” and evolve all over the world.

Anyway, I saw the GP yesterday and I am now on her list to be vaccinated. She says that they might have some vaccine next week and she is checking who is willing to be vaccinated. Right next to the UK there is country in which willing vaccine take up may be only as high as 50%. Great the UK is vaccinated, but much of its goods pass through an unvaccinated neighbour.

I am sure there will be many more twists and turns to this situation.

Please do not tempt fate with braggadocio….

Over promising again?