NaF PET/ CT hot topic research…

2.2. PET/CT Data Acquisition

All patients underwent 18F-NaF PET/CT. Data acquisition consisted of two parts: the dynamic part (dPET/CT studies) and the static part (whole-body PET/CT). dPET/CT studies were performed over the lower abdomen and the pelvic area after intravenous administration of maximum 250 MBq 18F-NaF for 60 min using a 24-frame protocol (10 frames of 30 s, 5 frames of 60 s, 5 frames of 120 s and 4 frames of 600 s). Whole-body, static imaging was performed in all patients with an image duration of 2 min per bed position for the emission scans after the end of the dynamic acquisition. A dedicated PET/CT system (Biograph mCT, S128, Siemens Co., Erlangen, Germany) with an axial field of view of 21.6 cm with TruePoint and TrueV, operated in a three-dimensional mode was used. The system allows the simultaneous acquisition of 56 transversal slices (1 bed position) with a theoretical slice thickness of 2.036 × 2.036 × 4 mm. A low-dose attenuation CT (120 kV, 30 mA) was used for attenuation correction of the dynamic emission PET data and for image fusion. A second low-dose CT (120 kV, 30 mA) was performed after the end of the dynamic series covering the area from the skull to the feet. All PET images were attenuation corrected and an image matrix of 400 × 400 pixels was used for iterative image reconstruction. Iterative image reconstruction was based on the ordered subset expectation maximization algorithm (OSEM) with 2 iterations and 21 subsets as well as time of flight (TOF).

Must have seriously fancy instrumentation to do this.

Christos Sachpekidis et al. in Cancers 2020, 12(5), 1335